Name | N-(2-Aminophenyl)-N'-phenylheptanediamide |
Synonyms | NKL22 NKL 22 NKL-22 HDACi-4b HDAC inhibitor IV Histone Deacetylase Inhibitor IV HISTONE DEACETYLASE INHIBITOR IV N-(2-Aminophenyl)-N'-phenylheptanediamide N-(2-Aminophenyl)-N'-phenylheptanediamide N1-(2-AMinophenyl)-N7-phenylheptanediaMide |
CAS | 537034-15-4 |
Molecular Formula | C19H23N3O2 |
Molar Mass | 325.4 |
Density | 1.212±0.06 g/cm3(Predicted) |
Melting Point | 159-161°C |
Boling Point | 627.9±40.0 °C(Predicted) |
Solubility | DMSO, Methanol |
Appearance | Beige solid |
Color | Off-White to Pale Beige |
pKa | 14?+-.0.70(Predicted) |
Storage Condition | -20°C Freezer |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.073 ml | 15.366 ml | 30.731 ml |
5 mM | 0.615 ml | 3.073 ml | 6.146 ml |
10 mM | 0.307 ml | 1.537 ml | 3.073 ml |
5 mM | 0.061 ml | 0.307 ml | 0.615 ml |
biological activity | NKL 22 is a selective HDAC inhibitor with an IC50 of 78 µm. |
Target | Value |
HDAC (Cell-free assay) | 78 μM |
Use | Histone deacetylase inhibitor IV. A cell-permeable pimeloylanilide compound that acts as a FXN-(frataxin gene specific HDAC inhibitor. |